Optimization of Extraction Process of Yunpitongbian Decoction by Response Surface Methodology / 中国药师
China Pharmacist
; (12): 777-780, 2017.
Article
in Zh
| WPRIM
| ID: wpr-610188
Responsible library:
WPRO
ABSTRACT
Objective: To optimize the extraction process of Yunpitongbian decoction.Methods: With the extraction yield and the contents of hesperidin and atractylenolide Ⅲ as the comprehensive evaluation indices, and based on the results of single factor tests, Box-Behnken response surface methodology was used to optimize the extraction process with the extraction duration, extraction times and liquid-solid ratio as the independent variables.Results: The optimum processing conditions were as follows: extracted three times with 15-fold amount of solvent and extraction time of 66 min.The measured value of comprehensive score was 1.198 40, which was close to the predicted value of 1.204 78.Conclusion: The optimized extraction process of Yunpitongbian decoction is simple and feasible with good predictability.
Full text:
1
Index:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
China Pharmacist
Year:
2017
Type:
Article