Functional Bowel Disorders, Are They Really Functional? / 胃肠病学

ABSTRACT

Functional bowel disorders (FBD) refer to a set of bowel symptoms related to the disorders of sensation, secretion and motility yet without a corresponding structural, histological, biochemical, or serological abnormalities.The pathogensesis of FBD is still not very clear.Whether these functional disorders reflect the inadequacy of our understanding of a disease or the limitation of our diagnostic testing is a question.With the development of the biomedical technology, some histological or biochemical changes were revealed, which supported the possibility that organic abnormality might exist in FBD.In this paper the progress of research on organic changes of irritable bowel syndrome and functional constipation was reviewed.