Relationship between Helicobacter Pylori Infection and Blood Lipid Metabolism and Atherosclerosis / 现代检验医学杂志

ABSTRACT

Objective To investigate the correlation between Helicobacter pylori (Hp) infection and blood lipid metabolism and atherosclerosis.Methods From October 2015 to October 2020,200 cases of Hp positive subjects were observed as observation group and 200 cases of Hp negative subjects as the control group,all subjects were blood lipid levels of vascular ultrasound and other related checks.Results The levels of total cholesterol (TC) (5.68± 1.46 mmol/L),triglyceride (TG) (1.58 ± 0.76 mmol/L) and low density lipoprotein cholesterol (LDL-C),and the difference was statistically significant (t=6.12,7.69,5.64,all P＜0.05).The detection rate of carotid atherosclerotic plaque in the observation group was 66.00 ％,which was significantly higher than that in the control group (49.50％),the difference was statistically significant (x2=29.61,P＜0.05),and the observation group.The detection rate of stable plaque was 44.5 ％,which was significantly higher than that of the control group 22.5％,the difference was statistically significant (x2 =21.73,P＜0.05).Conclusion Hp infection can affect the level of lipid metabolism in patients,which is an important factor in the occurrence and development of atherosclerosis.