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Epidemiological study of antibody to pertussis toxin IgG in newborns in Shunyi District of Beijing in 2016 / 中华围产医学杂志
Chinese Journal of Perinatal Medicine ; (12): 589-593, 2017.
Article in Chinese | WPRIM | ID: wpr-611130
ABSTRACT
Objective To investigate the levels of antibody to pertussis toxin (PT) IgG in newborns in Shunyi Women and Children's Hospital of Beijing Children's Hospital in 2016.Methods A total of 419 newborns were enrolled in this study.Umbilical cord blood sample was collected from each subject and detected by enzyme-linked immunosorbent assay to measure the concentration of PT-IgG.Besides,all newborns were followed up to January 31,2017.Chi-square test was used for statistical analysis.Results The detectable rate of umbilical cord blood samples for PT-IgG accounted for 30.1% (126/419).The median antibody level was < 5 U/ml,and the 90th and the 95th percentile were 14.3 and 24.0 U/ml,respectively.No cases of pertussis occurred at the end of follow-up.Conclusions The newborns born in Shunyi Women and Children's Hospital of Beijing Children's Hospital are generally lack of protective PT antibody.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Perinatal Medicine Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Perinatal Medicine Year: 2017 Type: Article