Clinical efficacy and safety of microwave ablation and surgical resection of benign thyriod nodules: Comparative study / 中国介入影像与治疗学

ABSTRACT

Objective To compare the clinical curative effect and security between microwave ablation treatment and surgical resection of benign thyroid nodules.Methods The imaging and clinical data of 100 cases of patients with benign thyroid nodules were collected,44 cases with 53 nodules were treated by microwave ablation treatment (ablation group),and 56 cases with 60 nodules were treated by surgical resection (surgery group).The rates of nodule regression in 1,3,6,12months after treatment,the size and changes of benign thyroid nodules in patients treated with microwave ablation therapy,as well as postoperative adverse reactions,time of inhospital were observed.Results The rates of nodule regression in 1,3,6,12 months therapy group were 54.55 ％,72.73 ％,95.45 ％,95.45 ％,while the rates in surgeny group were 100 ％.In the 1,3 months after treatment,the rates of nodule regression in ablation group were lower than those in surgery group (both P＜0.001).In the 6,12 months after treatment,the rates had no statistically significant differences in both groups (both P=0.245).With the extension of observation time,the nodule volume of the patients treated with microwave ablation therapy had a tendency to continue to shrink,particularly in the first 6 months.The incidence of hypothyroidism in ablation group was lower than surgery group (P=0.019).The difference of the incidence s of hematoma,infection,voice hoarse,parathyroid injury were not statistically significant in both groups (all P＞0.05).The time of inhospital in ablation group was obviously shorter than that in surgery group (t=-8.499,P=0.001).Conclusion Microwave ablation treatment of benign thyroid nodules has guaranteed results.It has the following advantages such as less complications,small trauma,short hospitalization time.So it has a broad prospect in clinical application.