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Retrospective analysis of literatures about 5 145 cases of gastrointestinal Dieulafoy lesion in China / 中华消化杂志
Chinese Journal of Digestion ; (12): 462-465, 2017.
Article in Chinese | WPRIM | ID: wpr-612055
Responsible library: WPRO
ABSTRACT
Objective To explore the clinical characters,treatment and prognosis of gastrointestinal Dieulafoy lesion in China.Methods Dieulafoy was used as search term,the literatures about Chinese patients with Dieulafoy lesions from January 1998 to October 2016 were retrieved in the Chinese literature library including China National Knowledge Infrastructure,VIP network,Wanfang database and China Biology Medicine disc,and a total of 515 literatures,5 145 patients were enrolled and analyzed.The gender,age,geographical distribution,location of the lesion,treatment and prognosis of the disease were summarized.Results Among the 5 145 patients (male 3 959,female 1 186) with Dieulafoy disease,the ratio of male to female was 3.34∶1.00.The age was from 3 to 95 years,and mean age was 51 years.The lesion location was mainly in stomach (88.82%,4 570/5 145) and second was small intestine (8.28%,426/5 145).In stomach,the lesions were mainly located in gastric corpus,fundus and cardia.The small intestinal Dieulafoy lesions were mainly located in duodenum.The main manifests were sudden hematemesis,melena,and hematochezia.The treatments mainly was endoscopic treatment (72.56%,3 733/5 145),and second was surgery (25.27%,1 300/5 145).Among the5 145 patients withDieulafoy disease,5 099 patients (99.11%) were cured and 46 patients (0.89%) died.The proportions of endoscopic treatment,interventional therapy and first endoscopic treatment within 24 hours in tertiary hospitals were all higher than those of nontertiary (all P<0.01).The cure rate of tertiary hospitals (99.22%,3 674/3 793) was significantly higher than that of nontertiary hosptials (98.54%,1 421/1 442) (x2 =0.89,P<0.05) and the mortality was significantly lower than that of nontertiary hospitals (P< 0.05).Conclusions The male is more susceptible to Dieulafoy lesion which occurred at any age than the female in China.The predilection sites of Dieulafoy lesion were stomach and duodenum.The primary treatments were endoscopic treatment and surgery,and the disease usually had a good prognosis.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Digestion Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Digestion Year: 2017 Type: Article