Progress of statins' effect on endometrial carcinoma / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 570-573, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-612215
ABSTRACT
Statins are a class of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors, which are pervasively used to reduce blood cholesterol concentration in hypercholesterolemic patients and prevent cardiovascular diseases in clinic, duo to excellent drug efficiency and good safety. In recent years, increasing evidences have demonstrated that statins have potential anti-tumor effect through inhibiting cancer cells growth, invasion, metastasis, preventing angiogenesis, promoting cancer cells apoptosis and synergetically enhancing the effect of radiotherapy and chemotherapy. However, there are no domestic reports about statins' effect on endometrial carcinoma, additionally, conclusions of related foreign studies are inconsistent. This review summarized the effect of statins on endometrial carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2017
Type:
Article
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