Observation of the effect of atorvastatin calcium combined with aspirin in the treatment of cerebral infarction / 中国基层医药

ABSTRACT

Objective To investigate the effect of atorvastatin calcium combined with aspirin in the treatment of patients with cerebral infarction.Methods 112 cases of cerebral infarction were randomly divided into two groups according to the digital table.The patients of the two groups were given conventional treatment,the control group was treated with aspirin enteric-coated tablets,the observation group was given atorvastatin calcium tablets combined wth aspirin enteric-coated tablets.The two groups were treated for 3 months.The clinical effect,blood rheology and NIHSS score of the two groups were investigated.Results After treatment,the total efficiency of the observation group was 80.4% compared with the control group of 55.4%,the difference was statistically significant (x2=4.012,P<0.05);after the treatment,the observation group of fibrinogen,plasma viscosity,whole blood viscosity at high shear rate and low blood viscosity compared with the control group,the differences were statistically significant (t=5.724,5.986,9.364,12.663,all P<0.05);the NIHSS score of the observation group compared with the control group,there was significant difference (t=6.358,9.554,all P<0.05).Conclusion Atorvastatin calcium combined with aspirin in the treatment of cerebral infarction can significantly improve the patients' blood rheology indicators and NIHSS score,improve the clinical treatment effect,has great clinical significance.