Study on the differences of Ketamine and Fentanyl in pediatric regional anesthesia / 中国生化药物杂志

ABSTRACT

Objective To explore the difference and clinical effect in pediatric regional anesthesia with ketamine and fentanyl.MethodsThe clinical data of 60 cases of children with surgical treatment from June 2014 to December 2015 in Longde People's Hospital were retrospectively analyzed and randomly divided into two groups,with 30 cases in each group.The control group was given simple ketamine anesthesia;The intervention group was given ketamine combined with fentanyl anesthesia, of children with breathing,After anesthesia,the heart rate, respiratory,arterial pressure and other indicators and the anesthetic effect of the two groups were comprehensively evaluated.ResultsIn the intervention group after anesthesia, heart rate, respiratory rate, mean arterial pressure and pulse oxygen saturation was significantly better than the control group, there was statistical significance (P<0.05);and wake-up time in the intervention group, the dosage of ketamine and ketamine bolus times was significantly lower than the control group,there was statistical significance (P<0.05).ConclusionThe regional anesthesia operation were given ketamine and fentanyl assisted anesthesia, can stabilize children's heart rate, respiratory rate, shorten postoperative awake time, reduce anesthetic dosage, higher safety, anesthetic effect, can be widely applied in clinical.