Effect of weifu'an combined with dietary improvement on immune function and quality of life in patients with advanced gastric cancer chemotherapy / 中国生化药物杂志

ABSTRACT

Objective To investigate the effect of Weifu'an combined with dietary improvement on immune function and quality of life in patients with advanced gastric cancer chemotherapy.MethodsAnalysis of hospital, 70 cases of Ⅲ~Ⅳ period clinical medical records and treatment in patients with advanced gastric cancer;According to random number table method will be divided into the control group (chemotherapy using OLF) and observation group (chemotherapy combined Weifu'an combined dietary improvement), and 35 cases statistics of two groups of clinical curative effect and adverse reactions after the treatment of four course, carr's quality of life (KPS) score was used to ealuate treatment in both groups before and after the survival quality.Detection in the two groups before and after treatment in patients with immune function.ResultsThe control rate of clinical disease was 68.57% in the observation group and 60.0% in the control group, there was no significant differemce.The KPS score of the observation group and the control group was significantly higher than that of the control group before the treatment and the KPS score of the observation group was significantly higher than that of the control group(P<0.05).Compared with the observation group, the levels of CD4+/CD8+ and NK cells in the control group were significantly lower than those in the control group, the difference was statistically significant (P<0.05).The adverse reaction rate was 37.14% in the observation group and 68.57% in the control group,the difference was statistically significant(P<0.05).ConclusionWeifu'an combined dietary improvement can reduce adverse reactions, immune function and help to improve the patients quality of life.