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Effects of Embolization and Clipping Therapy on Cognitive Function in Patients with Intracranial Aneurysms / 现代生物医学进展
Progress in Modern Biomedicine ; (24): 4498-4501,4509, 2017.
Article in Zh | WPRIM | ID: wpr-614879
Responsible library: WPRO
ABSTRACT
Objective:To evaluate the effects of endovascular embolization and microsurgical clipping on cognitive function in patients with intracranial aneurysm.Methods:A total of 80 patients with intracranial aneurysms,who were treated in Chongqing Hospital of Traditional Chinese Medicine from March 2014 to September 2015,were selected and randomly divided into control group(n=40) and experimental group (n=40).The control group was treated with microsurgical clipping,and the experimental group,with endovascular embolization.The postoperative cognitive function was assessed by the mini mental state examination scale (MMSE),and length of stay,in-hospital mortality rate,mortality rate in 1 year and the incidence of postoperative adverse reactions were compared between the two groups.Results:The total score (26.78± 0.85) of MMSE in the experimental group was higher than that (22.25± 0.63) of the control group (P<0.05).The cognitive dysfunction rate (37.50%) of the experimental group was lower than that (55.00%) of the control group (P<0.05).The length of stay [(6.7± 3.9) days] of the experimental group was lower than that [(9.6± 4.5) days] of the control group(P<0.05).There were no significant differences in in-hospital mortality rate and mortality rate in 1 year,and the incidence of adverse reactions between the two groups (P>0.05).Conclusion:Endovascular interventional therapy can improve the cognitive function of the patients with intracranial aneurysms and shorten the length of hospital stay.
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Full text: 1 Index: WPRIM Language: Zh Journal: Progress in Modern Biomedicine Year: 2017 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Progress in Modern Biomedicine Year: 2017 Type: Article