The Progress in the Animal Modeling of Pulmonary Arterial Hypertension / 现代生物医学进展
Progress in Modern Biomedicine
;
(24): 4979-4981,4978, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-615081
ABSTRACT
Animal models of pulmonary artery hypertension (PAH),aiming to simulate human characteristics of the disease,have contributed extensively to understanding the pathophysiology of PAH and the investigation of experimental treatments.The classical models include monocrotaline models,chronic hypoxia model and so on,more new models were investigated in recent years.These animal models were not able to perfectly mimic human pathological characteristics of PAH because of the defect in different aspects.In this review,both typical and novel methods of PAH modeling were summarized and evaluated to provide a suitable guidance for the settlement of animal models which can meet human characteristics comprehensively.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
/
Prognostic study
Language:
Chinese
Journal:
Progress in Modern Biomedicine
Year:
2017
Type:
Article
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