Clinical application and research progress in recombinant human growth hormone / 国际儿科学杂志

ABSTRACT

Growth hormone is a protein secreted by the anterior pituitary acidophilic cell,which directly or indirectly affects growth and metabolism via insulin-like growth factor.Growth hormone can be applied to the target cells of various tissues,and has extensive physiological functions.With the development of further clinical studies,the application of recombinant human growth hormone is no longer limited to children dwarfism treatment,and it also has clinical significances in the adult growth hormone deficiency,neurological diseases such as hypoxic-ischemic encephalopathy,traumatic brain injuries,cerebral palsy,Alzheimer's disease and other diseases such as bum and assisted reproduction.This paper reviews current clinical application and research progress in recombinant human growth hormone at home and abroad.