Progress in research of status epilepticus in children / 国际儿科学杂志

ABSTRACT

Status epilepticus (SE) is one of the most common neurologic emergencies and can be associated with significant morbidity and mortality if not treated promptly and aggressively.Actively,quickly and effectively controlling seizures is the key to save patient's life and improve the prognosis,which is particularly important in children.The status epilepticus is currently most recognized as:a single epileptic seizure lasting for more than 5 minutes during each seizure,or more than 2 episodes,with interictal neurological function that can not return to normal baseline.In 2015,ILAE updated the new definition of SE,which redefined the time of onset to diagnose SE and also redefined the time of onset to cause damage to brain.The new definition made clinical treatment more active and positive,and reduced the incidence of complications and sequelae.The purpose of this article is to summarize the definition,etiology,classification,physiopathologic mechanism,treatment and prognosis of SE.Also we review the published reports to provide the reference for early clinical diagnosis and standard treatment of SE.