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18F-FDG PET/CT Manifestation and Staging of Nasal Extranodal NK/T-cell Lymphoma / 中国医学影像学杂志
Chinese Journal of Medical Imaging ; (12): 487-490,495, 2017.
Article in Zh | WPRIM | ID: wpr-615294
Responsible library: WPRO
ABSTRACT
Purpose To investigate the 18F-FDG PET/CT manifestation ofextranodal NK/T-cell lymphoma (ENKTCL) for providing important reference for the early diagnosis,accurate staging and guiding treatment of the disease.Materials and Methods The imagings and clinical data of twenty-six patients with nasal ENKTCL were analyzed retrospectively.The diagnosis was confirmed by pathological biopsy and immunohistochemistry.The distribution and metabolic signs of the lesions were summarized,and the influence of PET/CT on nasal ENKTCL staging was analyzed.Results Totally 102 positive lesions were detected in 26 patients.The SUVmax of all lesions was 12.2±5.4 (3.2-28.5).The primary lesions were mainly located in the nasal cavity (16/26,61.5%).Facial soft tissue and paranasal sinus tissue involvement were most common adjacent invasions.The distribution of the remaining affected tissues and organs in the whole body showed no obvious regularity.Lymph node involvement was most common in cervical lymph nodes.The lesion detection rates of PET/CT and conventional imaging (plain scan/enhanced CT,plain scar/ enhanced MRI,ultrasound,etc.) in lymph node and extranodal organ involvement were 96.7% and 65.5%,respectively,and the accuracy of staging were 92.3% and 73.1%,respectively.Clinical stages were changed in 15 patients (57.7%)because of PET/CT examination,among which,the staging was improved in twelve cases for finding more lesions,the staging of the suspicious lesions were reduced and the nature was defined in three cases because of their lack of metabolism on the PET/CT,and the treatment plan was affected in nine cases for staging adjustment.Conclusion 18F-FDG PET/CT can accurately show the distribution of nasal ENKTCL lesions.Compared with the conventional imaging methods,more lymph nodes and extranodal organ involvement can be detected by 18F-FDG PET/CT,which makes the staging more accurate and guides the clinical treatment more effectively.
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Full text: 1 Index: WPRIM Type of study: Screening_studies Language: Zh Journal: Chinese Journal of Medical Imaging Year: 2017 Type: Article
Full text: 1 Index: WPRIM Type of study: Screening_studies Language: Zh Journal: Chinese Journal of Medical Imaging Year: 2017 Type: Article