Effect of Short-Term Partial Enteral Nutrition on the Treatment of Younger Patients with Severe Crohn's Disease
Gut and Liver
;
: 87-93, 2015.
Article
in English
| WPRIM
| ID: wpr-61570
ABSTRACT
BACKGROUND/AIMS:
To analyze the effect of short-term supportive temporary partial enteral nutrition therapy for treating severe pediatric Crohn's disease (CD).METHODS:
We conducted a prospective, open-label study in pediatric patients with CD (n=78) from January 2007 to December 2011. The CD patients were divided into three groups according to disease severity (mild, moderate, and severe). Seventeen patients with severe CD received short-term partial enteral nutrition (SPEN) in addition to their general diet for 4 weeks after the induction of remission with medical treatment. This SPEN group was further divided into two groups by age ( or =13 years). Nutritional parameters and Pediatric Crohn's Disease Activity Index scores were analyzed at the initial enrollment and following 1 year of treatment for all groups.RESULTS:
Nutritional status improved substantially after 1 year of treatment in the severe CD group. Nutritional status in the SPEN group improved considerably more than that in the non-SPEN group. Additionally, the or =13-year-old group.CONCLUSIONS:
SPEN may be effective in pediatric patients with severe CD for improving nutritional status and moderating disease severity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Crohn Disease
/
Nutritional Status
/
Prospective Studies
/
Treatment Outcome
/
Enteral Nutrition
Type of study:
Observational study
Limits:
Adolescent
/
Female
/
Humans
/
Male
Language:
English
Journal:
Gut and Liver
Year:
2015
Type:
Article
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