Application of omeprazole combined with psychological intervention in the treatment of peptic ulcer disease / 中国生化药物杂志

ABSTRACT

Objective To explore the clinical application of omeprazole combined with psychological nursing intervention in the treatment of peptic ulcer. Methods 80 patients with peptic ulcer treated in our hospital from April 2014 to October 2016 were selected, and randomly divided into control group and experimental group, 40 patients in each group. The control group was treated with omeprazole, amoxicillin and tinidazole, and the experimental group was treated with psychological nursing intervention based on the treatment of the control group. Both groups were treated for four weeks in a row. The clinical efficacy and the recurrence rate after treatment were followed up to half a year after treatment in two groups were compared. Results After four weeks of treatment, the total effective rate in experimental group was 92.5％, which was significantly higher than that in the control group (P<0.05). After six months of follow-up, the recurrence rate of patients in the experimental group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion Patients with peptic ulcer treated with omeprazole combined with psychological nursing intervention, the effect is significant, relieve the patient's clinical symptoms, effectively improve the clinical cure rate of peptic ulcer recurrence rate is low, high security, is worth popularization and application in clinic.