The correlation between serum CXCL10 level and the severity of OSAS in male patients / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 696-700, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-616046
ABSTRACT
Objective:
To investigate the correlation between serum CXCL10 level and the severity of obstructive sleep apnea syndrome(OSAS) in male patients.Methods:
52 male patients and 41 control volunteers were enrolled.Polysomnography was processed to monitor the AHI scores.Serum CXCL10 level was determined by ELISA.The correlation between serum CXCL10 level and AHI scores was analyzed statistically.Results:
Serum CXCL10 level(ng/ml) in the OSAS groups was significantly higher than that in the control group [99.18 (70.46-158.01) vs 64.13 (53.5-73.6),P < 0.001].Multivariate logistic regression analysis demonstrated that serum CXCL10 level was the only independent predictor of OSAS(OR1.021;95% CI1.009-1.035;P <0.001).The serum CXCL10 level was positively correlated with the severity of OSAS [CXCL10 level in mild OSAS82.7 (56.76-145.51);in moderateOSAS 113.28 (87.15-162.67)].Serum CXCL10 level was independently correlated with AHI scores(r =0.476,P < 0.001).Conclusion:
Serum CXCL10 level was independently associated with the occurrence and the severity of OSAS.Serum CXCL10 level can be used as a biomarker to diagnose the OSAS and further to assess the severity of OSAS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS