Analysis of Stability of Drug and Rationality of Drug Selection in 5770 Parenteral Nutrition Medical Or-ders of Our Hospital / 中国药房

ABSTRACT

OBJECTIVE:To provide reference for rational use of parenteral nutrition. METHODS:Combining with the pa-tients'nutritional status,clinical diagnosis and lab examination,5770 parenteral nutrition medical orders were collected from our hospital during May 2015-Apr. 2016,and then analyzed in respects of the stability of drug use,rationality of drug selection and pharmacoeconomics. RESULTS:The qualified stability of nutrient solution in 5770 parenteral nutrition medical orders accounted for 89.46%. The rates of reasonable drug selection in patients with abnormal liver function,renal function,hyperemesis gravidarum,pan-creatitis,complete fasting,long term parenteral nutrition (>14 d) and triacylglycerol >4.5 mmol/L were 76.19%,63.16%, 75.00%,78.95%,65.95%,64.06%and 50.00%,respectively. Four kinds of drugs were with same effect and dose,price difference between 4-34 times,the rate of inappropriate drug selection ranged 7.58%-61.64%. CONCLUSIONS:Parenteral nutrition design need to not only consider about nutritional status,clinical diagnosis and lab examination,but also take into account high efficiency,safety, economy and the stability of whole nutrient solution.