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Research progress of Ghrelin and obesity,insulin resistance and type 2 diabetes mellitus / 中国糖尿病杂志
Chinese Journal of Diabetes ; (12): 666-669, 2017.
Article in Chinese | WPRIM | ID: wpr-616520
ABSTRACT
Ghrelin is a small active peptide secreted by gastric fundus cell. As an endogenous ligand of growth hormone receptor,it helps to promote growth hormone secretion,increase food intake and participate in energy metabolism. Recently,studies have indicated that Ghrelin,together with other peripheral signals,participate in the regulation of glucose and lipid metabolism. Insulin resistance (IR) is an important pathophysiological basis of the development of type 2 diabetes mellitus (T2DM),while obesity is the common risk factor of both IR and T2DM. It has been confirmed that Ghrelin has a close and complex connection with obesity and T2DM. Further study about Ghrelin may open up a new way to the diagnosis and treatment of obesity and T2DM.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Diabetes Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Diabetes Year: 2017 Type: Article