Occupational Reproductive Function Abnormalities and Bladder Cancer in Korea
Journal of Korean Medical Science
;
: S41-S45, 2010.
Article
in English
| WPRIM
| ID: wpr-61694
ABSTRACT
The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Korean workers. In 1995, 23 of the 33 workers (25 female and 8 male workers) who were exposed to 2-bromopropane during the assembly of tactile switch parts developed reproductive and/or hematopoietic disorders. A total of 17 (68%) workers were diagnosed with ovarian failure. Two of the eight male workers experienced azoospermia and four workers experienced some degree of oligospermia or reduced sperm motility. In summary, 2-bromopropane poisoning caused severe reproductive effects in Korean workers. The prognosis was poor for reproductive dysfunction. A few cases of occupational bladder cancer have been reported in Korea, whereas other cancers of the urinary tract have not been reported after occupational exposure. A few cases of benzidine-induced cancer have been reported in Korea and 592 workers in Japan have received compensation for benzidine and beta-naphthylamine-induced cancer. In conclusion, a few cases of benzidine-induced occupational bladder cancer have been reported in Korea. However, benzidine-induced bladder cancer will likely be an important occupational health issue in Korea in the coming years.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligospermia
/
Sperm Motility
/
Benzidines
/
Urinary Bladder Neoplasms
/
Occupational Exposure
/
Primary Ovarian Insufficiency
/
Azoospermia
/
Republic of Korea
/
Hydrocarbons, Brominated
/
Infertility
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS