Relationship Between Blood Big Endothelin Level and Contrast-induced Acute Kidney Injury in Patients With Emergent Percutaneous Coronary Intervention / 中国循环杂志
Chinese Circulation Journal
;
(12): 633-637, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-617058
ABSTRACT
To explore the relationship between blood level of big endothelin and contrast-induced acute kidney injury (CI-AKI) in patients with emergent percutaneous coronary intervention (PCI). Methods:
A total of 1061 consecutive patients received emergent PCI in our hospital from 2013-01 to 2015-06 were enrolled. According to blood levels of big endothelin, the patients were divided into 2 groups Normal big endothelin group, n=236 and Elevated big endothelin group, n=825. The baseline condition, procedural features, occurrence rate of CI-AKI and composite endpoint events at 6 and 12 months post-operation were studied which including nonfatal myocardial infarction, revascularization, stroke and all-cause death. The risk factors for CI-AKI occurrence were identified by Logistic analysis.Results:
The overall occurrence rate of CI-AKI was 22.7% (241/1061). Compared with Normal big endothelin group, Elevated big endothelin group had the higher incidence of CI-AKI, increased composite endpoint events at 6 and 12 months post-operation with P=0.041, P=0.040 and P=0.021, respectively. With adjusted covariates, elevated blood level of big endothelin, no matter as a continuous variable or categorical variable had the enhanced risk of CI-AKI incidence in patients after emergent PCI.Conclusion:
Elevated blood level of big endothelin may significantly increase the risk of CI-AKI in patients with emergent PCI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2017
Type:
Article
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