Phenylboronic acid-based glucose-responsive materials: synthesis and applications in insulin delivery / 中国药科大学学报
Journal of China Pharmaceutical University
;
(6): 259-267, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-617464
ABSTRACT
Glucose-sensitive materials have attracted much interest due to their potential application in diabetes treatment in recent years.Phenylboronic acid-based glucose-responsive polymers,which possess continuous glucose sensitivity and good stability,have been most widely used in self-regulated insulin delivery.This review covers the recent advances in PBA-functionalized nanogels (microgels),micelles,vesicles and nanoparticles.Synthesis and application of these nanomaterials are discussed.With the development of PBA-regulated polymers,these nanomaterials will migrate from laboratory to clinical use in the near future.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of China Pharmaceutical University
Year:
2017
Type:
Article
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