Compatible Stability of Cyclophosphamide and Mesna Admixture for Injection in 4 Commonly Used Infusions / 中国药师
China Pharmacist
; (12): 1331-1333, 2017.
Article
in Zh
| WPRIM
| ID: wpr-617471
Responsible library:
WPRO
ABSTRACT
Objective: To study the compatible stability of cyclophosphamide (CTX) and Mesna admixture for injection in 4 commonly used infusions (5% glucose injection,0.9% sodium chloride injection,fructose injection and xylitol injection) at different temperatures.Methods: An HPLC method was adopted to determine the contents of CTX for injection in 24h respectively under 5℃ and 25℃.The appearance and pH value of the admixture were investigated.Results: No significant changes of appearance, pH value or content of the admixture were found out in 24h under 5℃ and 25℃.Conclusion: CTX and Mesna admixture for injection is compatible with the 4 commonly used infusions under 5℃ and 25℃ for clinical use in 24 h.
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacist
Year:
2017
Type:
Article