A new challenge to the diagnosis and treatment of sepsis: Persistent inflammation immuno-suppression catabolism syndrome / 医学研究生学报

ABSTRACT

The early mortality of sepsis patients has been largely decreased since the publication of the Surviving Sepsis Campaign guidelines.However, the poor long-term prognosis, high 3-year mortality, impaired mental and physical functions, and tremendous financial burden constitute a new challenge to the treatment of sepsis.Persistent inflammation immuno-suppression catabolism syndrome (PICS) is known to be a definite factor affecting the long-term prognosis of sepsis.This article presents a systematic review of the concept, pathogenesis and treatment strategies of PICS, hoping to provide a new approach to the diagnosis and management of sepsis.