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Long term effect of calcium carbonate bone cement combined with bFGF in repairing pulp chamber perforation / 国际生物医学工程杂志
International Journal of Biomedical Engineering ; (6): 169-172, 2017.
Article in Chinese | WPRIM | ID: wpr-617940
ABSTRACT
Objective To investigate the long-term efficacy of calcium phosphate cement combined with bFGF in repairing pulp chamber perforation and to analyze the correlation between the diameter of the perforation and the curative effect.Methods 75 patients with pulp chamber perforation (82 teeth) were enrolled and divided into the observation group and the control group according to the repair material and method.A series of subgroups were also modeled according to the diameter of the perforation,which include the control group A (≤ 1.5 mm),control group B (1.6~3 mm) and control group C (>3 mm),as well as the observation group A (≤ 1.5 mm),observation group B (1.6~3 rmm) and observation group C (>3 mm).The observation group was treated with calcium phosphate cement combined with bFGF,and the control group was treated with calcium phosphate cement alone.Results The total effective rate of the observation group was 97.8%,which was significant higher than 80.6% in the control group (P<0.05).The cure rate of the observation group A was 100%,which was significant higher than 73.3% in the observation group B and 41.7% in the observation group C (all P<0.05).The total effective rates of the observation group A and B were significantly higher than 91.7% in the observation group C (all P<0.05).The cure rate of the control group A was 92.9%,which was significant higher than 60.0% in the control group B and 25.0% in the control group C (all P<0.05).The total effective rates of the control group A (100%) and B (90.0%) were significantly higher than 91.7% in the control group C (all P<0.05).Conclusions Calcium phosphate cement combined with bFGF in repairing the pulp chamber perforation was significantly better than calcium phosphate cement alone.The cure rate of perforation repairing is closely related to the perforation size.The perforation with small diameter may achieve a better repairing effect.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Biomedical Engineering Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Biomedical Engineering Year: 2017 Type: Article