The effect of basic fibroblast growth factor on the proliferation of gingiva-derived mesenchymal stem cells / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 603-606, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-618623
ABSTRACT
Objective:
To investigate the effect of basic fibroblast growth factor(bFGF) on the proliferation of gingiva-derived mesenchymal stem cells(GMSCs) in vitro.Methods:
GMSCs were isolated from healthy gingival tissue samples and identified.GMSCs of passage 4 were treated by bFGF at 0,0.5,1,5,10,20 ng/ml respectively for 1-9 d.The proliferation of the cells was evaluated using CCK-8 kit.Results:
bFGF at 0.5-20 ng/ml increased GMSCs proliferation.0.5-10 ng/ml of bFGF showed dose and time dependant proliferation promoting effect on GMSCs.Conclusion:
bFGF can increase GMSCs proliferation ability in a dose and time dependant manner.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2016
Type:
Article
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