Simultaneous Determination of Naringin and Neohesperidin in Weitong Pills by HPLC / 中国药师
China Pharmacist
;
(12): 1112-1114, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-619741
ABSTRACT
Objective:
To establish a method for the content determination of naringin and neohesperidin in Weitong pills.Methods:
An HPLC method was adopted.The determination was performed on an Agilent TC-C18 column with the mobile phase consisting of acetonitrile-water(20∶80)at the flow rate of 1.0 ml·min-1.The detection wavelength was set at 283nm.The column temperature was 30 ℃.Results:
Naringin and neohesperidin respectively within the concentration range of 0.027-4.552 μg (r=0.999 9) and 0.029-4.016 μg(r=0.999 8) had good linear relationship with the peak area, the average recovery was 102.19% and 103.60%,and the RSD was 2.88% and 1.79%(n=9), respectively.Conclusion:
The method is simple,accurate and reproducible, and suitable for the content determination of naringin and neohesperidin in Weitong pills.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2017
Type:
Article
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