Progress in research of the DrrAB efflux system of Streptomyces peucetius / 中国人兽共患病学报
Chinese Journal of Zoonoses
;
(12): 454-458, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-620011
ABSTRACT
The bacterium Streptomyces peucetius produces doxorubicin and daunorubicin,and the two widely used anticancer antibiotics.Two open reading frames,drrA and drrB,were proposed to encode for an ABC (ATP-binding cassette) type of permease that carries out export of the antibiotic ABC (ATP binding cassette)-type transporter for the exportation of these two antibiotics.In this paper,the structure,expression and interaction of DrrA and DrrB protein and the research progress of the assembly and multi drug efflux function of DrrAB are briefly reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Zoonoses
Year:
2017
Type:
Article
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