Structures and functions of tripartite-motif proteins / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
;
(12): 479-484, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-620083
ABSTRACT
Members of the tripartite-motif (TRIM) protein family share a highly conserved domain architecture known as RBCC motif,which is composed of a RING finger domain,one or two B-box domains,a coiled-coil domain as well as diverse types of C-terminal regions.TRIM proteins can not only maintain the normal physiological functions of the body,but also regulate the development of various diseases.In the current review,we focus on recent advances in the structures of TRIM proteins and their functions in the development of viral infection,cancer and neurodegenerative disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Microbiology and Immunology
Year:
2017
Type:
Article
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