Research progress in myocardial fibrosis regulated by microRNAs and their pathways / 中华地方病学杂志
Chinese Journal of Endemiology
;
(12): 464-468, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-620101
ABSTRACT
Myocardial fibrosis is a pathological process characterized by fibroblast proliferation and collagen deposition,which occurs in the normal structure of the myocardium.MicroRNAs (miRNAs) are a class of endogenous,non-coding RNA of approximately 22 nucleotides in length,regulating gene expression at posttranscriptional level by complementary pairing with the target gene mRNA.Recent studies have showed that miRNAs play an important role in the formation of myocardial fibrosis,therefore,much attention has been paid to miRNAs as they may serve as targets for prevention and treatment of myocardial fibrosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endemiology
Year:
2017
Type:
Article
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