Application of induced pluripotent stem cells in retinal diseases / 眼科新进展
Recent Advances in Ophthalmology
;
(6): 587-590, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-620111
ABSTRACT
Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cells that can be generated from adult somatic cells.They have similar characteristics and function to embryonic stem cells (ESCs).Over the past decade,iPSCs were widely concerned in regenerative medicine and stem cell field.Especially the patient specific iPSCs have several advantages over ESCs,such as convenient source,do not exist immune rejection and ethical issues,even keep certain individual genotype.At present,tremendous progress have been made about the application of iPSCs in a variety of retinal diseases.Here,this article reviews pluripotent stem cell sources of RPE,photoreceptors and retinal ganglion cells and current transplantation strategies,the safety problems and prospects.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Recent Advances in Ophthalmology
Year:
2017
Type:
Article
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