Diagnostic value of serum hyaluronic acid and laminin in patients with coronary heart disease complicated with myocardial infarction / 中国生化药物杂志

ABSTRACT

Objective To investigate the diagnostic value of serum hyaluronic acid and laminin in patients with coronary heart disease complicated with myocardial infarction.Methods 100 patients with coronary heart disease(CHD) were selected as the coronary heart disease group, and the patients with CHD and myocardial infarction(AMI) were selected as the infarct group in our hospital from July 2015 to July 2016.The levels of serum hyaluronic acid and laminin were compared between the two groups, and the levels of hyaluronic acid and laminin were analyzed.Results The expression of LN and HA in the infarction group were significantly higher than those in the coronary heart disease group(Pdouble branch lesions > single vessel disease(P<0.05).LN and HA expression in different coronary artery lesions in the infarction group were significantly higher than those in the coronary heart disease group(P<0.05).The expression of LN and HA in patients with anterior and inferior wall myocardial infarction were significantly higher than those in anterior wall and inferior wall infarction(P<0.05).Conclusion The increase of serum HA and LN in patients with coronary heart disease may cause acute myocardial infarction.