Study on Meconium Peritonitis Associated with Intrauterine Intestinal Perforation / 대한주산의학회잡지

ABSTRACT

OBJECTIVE: This study was aimed to study clinical characteristics of patients with intrauterine meconium peritonitis, differences of various factors in between those who required operation and those who did not, risk factors leading into operation, and prognosis in the era of high prenatal diagnosis. METHODS: A retrospective review of 53 patients was done. Various factors for operation group (n= 41) and non-operation group (control, n=12) were compared. The risk factors for operation were analyzed by logistic regression analysis. RESULTS: The mean gestational age and birth weight for 53 including 41 (77%) of prenatally diagnosed cases were 36+/-3.4 weeks and 2,819+/-755 g, respectively. The most frequent antenatal sonographic finding was calcification. The most common etiology was ileal atresia. The first and full feeding was at 1.4+/-1.5 and 4.2+/-1.9 day, respectively for control (11.3+/-10.9 and 32.3+/-24.7 day). Risk factors for operation included requirement of mechanical ventilation and cesarean delivery. Overall survival rate was 94%. Survivial rate of those who were antenatally diagnosed was 97.6% in comparison to 83.3% who were not. The growth at 12 months was satisfactory. CONCLUSION: Favorable outcome of intrauterine meconium peritonitis is reassuring and stems from multidisplinary team approach.