Clinical application of five kinds of antihypertensive drugs in department of cardiology / 中国生化药物杂志

ABSTRACT

Objective To study and analyze the clinical application of five kinds of antihypertensive drugs in Department of cardiology. Methods In our hospital from January 2015 to December 2016 treated 100 cases of oral antihypertensive drugs in cardiovascular disease patients as the research object of this study, retrospective analysis of clinical data of patients, medication of patients, the system analysis of selected patients with medication, including patient name and the category, record the daily dose and the drug combination. Evaluation was made by using frequency index and index of utilization of drugs. The standard of rational drug use is drug utilization index (<1). Results After the corresponding analysis, the number of available urine drugs was 32 cases, the utilization rate was 32%. The number of use of beta blocking drugs was 28, with a utilization rate of 28%. The number of use cases of calcium antagonists was 20 cases, and the utilization rate was 20%. Angiotensin converting enzyme inhibitors were used in 14 cases, with a utilization rate of 14%. The use of angiotensin receptor Ⅱ blockers was 6 cases, with a utilization rate of 6%. Five of the three antihypertensive drugs were diuretic drugs, beta blockers and calcium antagonists. The highest frequency of use of metoprolol was 25%. The number of cases with furosemide was 13, and the frequency of medication was 13%. The number of drugs used in Extended Release Nifedipine Tablets was 12 cases, and the frequency was 12%. After the research, we can conclude that the combination of two or triple drugs is more effective in the combined use of hypertension. The utilization index of Hydrochlorothiazide Tablets and amlodipine tablets was greater than 1, and the other drugs met the standard of rational use. Conclusion The rational use of antihypertensive drugs can guarantee the effect of treatment to some extent, help patients to stabilize blood pressure, improve the quality of life of patients.