study of side effect of glucocorticoid in asthma patients at Allergic - MDLS Department of Bach mai hospital

ABSTRACT

Retrospective study on 1026 patients with asthma at Bach Mai Hospital from 1 January 1998 to 31 January 2002. Among them, 69.4% were 21 to 50 years old, with no different in sex. Hospitalized rate was highest in annual November. Glucocorticoid was used in all these patients with common kinds as solu-medrol 76.2%; prednisolone 67.7%; depersolone 44.3% và Pulmicort 7.6%. Rate of complication related to glucocorticoids was 28.7%. There were 24 types of symptom, including high blood glucose (11.5%), hypokaliemia (9.45%), hypertension (3.45%), gastric ulcer (2.83%), Cushing syndrome (2.53%). 7 systems damaged were endocrine (27.54%), musculoskeletal (4.28%), skin and mucous membrane (3.19%), gastrointestinal (4.96%), cardiovascular (3.7%), nervous and sense organs. There were 10 kinds of diseases and syndroms related to glucocorticoid use hypertension, gastric ulcer, Cushing syndrome, diabetes, ponosis, retarded development, urticaria, anapphylactic shock, cataract, metal disorders, secondary bacterial contamination