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Intermittent central nervous system irradiation and intrathecal chemotherapy for recurrent central nervous system leukemia in children
Journal of the Korean Pediatric Society ; : 1067-1072, 1993.
Article in Korean | WPRIM | ID: wpr-62467
ABSTRACT
Between 1986 and 1990, four children with recurrent CNS leukemia who had previous CNS prophylaxis therapy were treated with intermittent central nervous system irradiation and intrathecal chemotherapy (IIIC). There was no isolated CNS recurrence. One patient died form bone marrow relapse. Three patients are alive without evidence of disease for 3E3/12 year to 3E6/12 year after the diagnosis of recurrence of CNS leukemia. This experience suggests that IIIC may be an effective treatment for preventing the recurrence of CNS leukemia without any serious side effects.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Bone Marrow / Leukemia / Central Nervous System / Diagnosis / Drug Therapy / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Diagnostic study Limits: Child / Humans Language: Korean Journal: Journal of the Korean Pediatric Society Year: 1993 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Bone Marrow / Leukemia / Central Nervous System / Diagnosis / Drug Therapy / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Diagnostic study Limits: Child / Humans Language: Korean Journal: Journal of the Korean Pediatric Society Year: 1993 Type: Article