Biomarkers in cancer: An overview
Malaysian Journal of Medicine and Health Sciences
; : 23-32, 2008.
Article
in Ml
| WPRIM
| ID: wpr-627351
Responsible library:
WPRO
ABSTRACT
Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being developed to identify individuals with risk of cancer for early detection, to determine prognosis, to detect recurrence, to predict drug responses and to monitor response to treatment. There are several issues involved in the discovery of biomarkers and their development for clinical applications. This article provides a basic overview of the classes of biomarkers, the current status of molecular profiling and discusses the opportunities as well as challenges ahead to improve biomarker development.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Recurrence
/
Biomarkers
/
Neoplasms
Type of study:
Prognostic_studies
/
Screening_studies
Language:
Ml
Journal:
Malaysian Journal of Medicine and Health Sciences
Year:
2008
Type:
Article