The role of psychological resilience, severity of disease and treatment adherence in the prediction of health-related quality of life in patients with multiple sclerosis
Neurology Asia
;
: 263-268, 2015.
Article
in English
| WPRIM
| ID: wpr-628987
ABSTRACT
Objective:
This cross-sectional study aims to evaluate the impact of the disability status, psychological resilience, and treatment adherence on health-related quality of life (QOL) in patients with multiple sclerosis (MS).Methods:
One hundred MS outpatients, 80 women and 20 men, referred to a clinic of Shiraz University of Medical Sciences, were eligible to participate. MS was diagnosed by 2010 revised Mc-Donald criteria. The QOL and resilience were evaluated by the Medical Outcomes Study Short-Form (SF-36) and Connor-Davidson Resilience Scale (CD-RISC) respectively. Medication adherence and severity of disease were assessed by the Morisky Medication Adherence Scale (MMAS) and expanded disability status state (EDSS) scores respectively.Results:
Stepwise multiple regressions showed that in the first model, the disability status was the best predictor which accounted for 28.1% of the variance in QOL. In the second model, both the disability status and resilience explained 50.6% of the variation in QOL.Conclusion:
The findings showed that the severity of the disease is a strong predictor which has adverse effects on the physical component of health-related QOL in the patients with MS. Both psychological resilience and treatment adherence have positive influence on mental component of QOL in these patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Multiple Sclerosis
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Neurology Asia
Year:
2015
Type:
Article
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