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Differential gene expression of human adipose-derived stem cells in osteogenic induction
The Medical Journal of Malaysia ; : 9-10, 2008.
Article in Malayalam | WPRIM | ID: wpr-629914
ABSTRACT
Human adipose-derived stem cells (HADSC) have demonstrated the capacity of differentiating into bone depending on the specific induction stimuli and growth factors. However, investigation on stem cell characteristic after osteogenic differentiation is still lacking. The goal of this study was to investigate the differential expression of sternness and osteogenic genes in non-induced HADSC compared with HADSC after osteogenic induction using quantitative Real Time RT-PCR. Our results showed that OCT-4, REX-1, FZD9, OSC, RUNX, and ALP were up regulated after osteogenic induction. This may indicated that HADSCs after osteogenic induction still possessed some stemness properties.
Full text: Available Index: WPRIM (Western Pacific) Language: Malayalam Journal: The Medical Journal of Malaysia Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Malayalam Journal: The Medical Journal of Malaysia Year: 2008 Type: Article