Mouse bone marrow mesenchymal stem cells acquire CD45-CD106+ immunophenotype only at later passages
The Medical Journal of Malaysia
;
: 65-66, 2008.
Article
in Malayalam
| WPRIM
| ID: wpr-629981
ABSTRACT
Classically, MSC are identified by a CD45-CD106+ phenotype. In this study, we found that mouse MSC achieve this characteristic phenotype only at later passages. With increasing passages, CD45 (hematopoietic marker) expression shifts to negativity, whereas CD106 (vascular cell adhesion molecule-1) expression becomes increasingly positive. These results demonstrate that MSC cells cultured from mouse bone marrow acquire a classical MSC immunophenotype (CD45-CD106+) in later passages.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Malayalam
Journal:
The Medical Journal of Malaysia
Year:
2008
Type:
Article
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