Acute kidney injury following coronary artery bypass graft surgery in a tertiary public hospital in Malaysia: an analysis of 1228 consecutive cases
The Medical Journal of Malaysia
;
: 126-130, 2016.
Article
in English
| WPRIM
| ID: wpr-630749
ABSTRACT
Background:
Acute kidney injury (AKI) following cardiac surgery is well established but the reported incidence is variable due to varying definitions and criteria. Furthermore there is a paucity of such data from Southeast Asia.Objectives:
To determine the incidence of AKI, the associated risk factors, and its impact on early mortality and intensive care unit/hospital stay.Method:
This is a single centre retrospective observational study to evaluate outcomes on 1260 consecutive patients from a multi-ethnic Southeast Asian population who underwent a primary isolated coronary artery bypass graft (CABG) operation. Data was collected from the hospital’s electronic database and analysed using basic descriptive statistics and logistic regression.Results:
Overall incidence was 36.2% including 5.5% of patients who required renal replacement therapy (RRT). Multivariate analysis identified age, insulin-dependent diabetes mellitus (IDDM), baseline serum creatinine level (SCr), recent myocardial infarction (MI), cardiopulmonary bypass (CPB) time and intra-aortic balloon pump (IABP) use as independent risk factors for AKI. For patients who required RRT, the SCr and IDDM remained independent predictors. Early 30-day mortality (11.5% vs 0.9%) was significantly higher in patients who developed AKI following CABG. Similarly, AKI was associated with a slight but statistically significant increase in intensive care unit (ICU) and hospital stay.Conclusion:
Better prognostication and preventative strategies are required to better risk stratify patients undergoing CABG and optimise utilisation of limited healthcare resources.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acute Kidney Injury
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
The Medical Journal of Malaysia
Year:
2016
Type:
Article
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