Pilot study on metabolic syndrome prevalence among aging male / Монголын Анагаах Ухаан

ABSTRACT

INTRODUCTION: Main reasons of metabolic syndrome are obesity and overweighing, which are becoming a global worldwide problem. Obesity is both a prevalent condition worldwide and a well-known, modifiable risk factor for various diseases, including diabetes. In a recent review article, waist circumference (WC) and body mass index (BMI) were reported as established risk factors for diabetes. GOAL To define the prevalence of metabolic syndrome among Mongolian aging man living in Ulaanbaatar city MATERIALS AND METHODS: Randomly selected 180 men aged 35-90 years old were involved to this study. All were informed and written consent was given by each individual. The metabolic syndrome was defined by NCEP definition high blood pressure, high waist circumference, higher fasting sugar, triglyceride and HDL-cholesterol. Anthropometric parameters like waist circumference (WC), weight, height, blood pressure and blood chemical parameters like glucose, triglyceride (TG), HDL-cholesterol (HDL-Ch) were measured by automatic biochemical analyzer. RESULT AND DISCUSSION: Average age of all participants was 56.82±12.55 years and was divided in three age groups 35-60 (n=112), 61-74 (n=47), 74-90 (n=17). The characteristics of participants are shown Mongolian men in 38.8 % (70) of all participants had a metabolic syndrome and in compare to T.Baysgalan’s study, implemented in 2007 was higher. In our opinion it depends on our study participant’s age, because in our study number of elderly were predominating than mentioned survey. Waist circumference in metabolic syndrome group is higher than in healthy control group (p<0.05). Triglyceride level does not change with aging, but in our study participants, the TG level was negatively correlated with aging in metabolic syndrome group (r = -0.307). HDL-cholesterol is abundantly circulating molecule in human plasma and shows anti-atherogenic effect. In our participants HDL-Ch decreases with aging (r=-0.174). CONCLUSION: Our pilot study present that metabolic syndrome prevalence reaches 38.8% of total aged, male participants, and it is leads to implement and provide an investigation in large range, including urban and rural areas of the country.