Study on the Mechanism of Health Protection of Mongolian Medicine Polyginatum Odoratum / Монголын эм зүй, эм судлал
Mongolian Pharmacy and Pharmacology
;
: 22-26, 2017.
Article
in English
| WPRIM
| ID: wpr-631253
ABSTRACT
Objective:
To explore the effects of Polygonatum odoratum on body based on metabonomics.Methods:
The ultra performance liquid chromatography coupled with mass spectrometry (UPLC-MS) and principle component analysis(PCA) and orthogonal partial least squares discriminant analysis(OPLS-DA) were used to evaluate the changes of endogenous substances in rats after intragastric administration of Polygonatum odoratum.Results:
Significant differences between the control group and administration group were observed in PCA and OPLS-DA model. Five potential biomarkers between control group and administration group were identified. The relative content of Alpha-Tocotrienol, PC(141(9Z)/141(9Z)), Stearic acid, Theasapogenol A, Docosahexaenoic acid increased.Conclusion:
The biomarkers had many beneficial activities, so the Mongolian medicine Polygonatum odoratum had the function of health care. Key words Mongolian drug; Polygonatum odoratum; Biomarkers; UPLC-MS
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Mongolian Pharmacy and Pharmacology
Year:
2017
Type:
Article
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