Mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes (MELAS) in a two-year-old Filipino child
Acta Medica Philippina
;
: 88-92, 2011.
Article
in English
| WPRIM
| ID: wpr-631857
ABSTRACT
MELAS is a mitochondrial respiratory chain disorder characterized by progressive neurodegeneration associated with stroke-like episode, increased plasma lactate levels and distinctive findings on neuroimaging studies. Hence we onset of right-sided hemiplegia accompanied by lactic acidosis and CT-Scan findings of diffuse hypodensity of the cerebral white matter at the time of the stroke-like episode. The diagnosis was confirmed by mutation analysis on blood and hair which showed the typical mtDNA A3243G mutation. This is the first local report of a confirmed case of MELAS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Musculoskeletal Diseases
/
Mitochondrial Myopathies
/
Mitochondrial Encephalomyopathies
/
MELAS Syndrome
/
Muscular Diseases
Limits:
Female
/
Humans
Language:
English
Journal:
Acta Medica Philippina
Year:
2011
Type:
Article
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