Relationship of body mass index and related anthropometric measurements on the image quality of thallium-201 and technetium-99m sestamibi myocardial perfusion imaging
The Philippine Journal of Nuclear Medicine
;
: 11-17, 2012.
Article
in English
| WPRIM
| ID: wpr-632074
ABSTRACT
The study aims to determine the relationship of body mass index (BMI) and related anthropometric measurements on the image quality of Tl-201 and Tc-99m sestamibi myocardial perfusion scans (MPS). A total of 163 scans were analyzed. A blinded experienced physician performed visual analysis on the scans image quality on two different occasions. Quantitative parameter used was the heart-to-lung ratio (HLR). Regression analysis was done to determine the association of HLR with BMI and myocardial tracer uptake, ROC curves were generated to establish BMI and HLR cut-off points. Increasing BMI was associated with visually poorer images in the Tl-201 MPS group (p 0.003) but not for the Tc-99m MPS group (p 0.065). It was also associated with decrease HLR and myocardial tracer upatake for both tracers (p <0.001). ROC curves revealed BMI cut-off points of 28 (Tl-201 p 0.000; Tc99m sestamibi p 0.004) for both procedures; HR cut-off values of 3.0 for Tl-201 )p 0.295) and 2.5 for Tc-99m sestamibi (p 0.875). the image quality of Tl-201 scans begins to deteriorate at a BMI of 28 and HLR of 3.0 with myocardial count density reduction (less than or equal to 6000 counts) translating to visually poorer images. On the other hand , image quality of Tc-99m sestamibi scans also tend to deteriorate similarly at a BMI of 28. However, in contrast to Tl-201, the lower HLR cut-off of 2.5 suggests a relatively higher myocardial count density (greater than or equal to 9000 counts) rendering the image quality to be still satisfactory for subjective assessment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Diagnostic Imaging
/
Body Mass Index
/
Diagnostic Techniques and Procedures
/
Diagnosis
/
Myocardial Perfusion Imaging
/
Cardiac Imaging Techniques
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
The Philippine Journal of Nuclear Medicine
Year:
2012
Type:
Article
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