Diabetic polyneuropathy: mechanisms, prevention and treatment, are we doing too little, too late?

ABSTRACT

Diabetic polyneuropathy affects millions of people with diabetes. Although, the symptoms may be highly unpleasant, management have concentrated mainly on the disease process and other more visible or devastating secondary complications like diabetic ulcers and cardiac arrhythmia. Glycemic control remains the most important aspect in the management of diabetes that can deter or decelerate subsequent development of diabetic polyneuropathy. However, concentration on this aspect alone veers away from control of symptoms that may improve quality of life of patients.