Rosai-Dorfman disease presenting as recurrent nasal polyposis
Philippine Journal of Otolaryngology Head and Neck Surgery
;
: 22-24, 2014.
Article
in English
| WPRIM
| ID: wpr-632416
ABSTRACT
@#OBJECTIVES:
To present a case of Rosai-Dorfman disease in an individual with a 14-year history of recurrent nasal polyposis and discuss its clinical presentation, physical examination, radiologic findings, histopathologic characteristics and available treatment.METHODS:
Design:
Case ReportSetting:
Tertiary Government Hospital Patient OneRESULTS:
A 26-year-old Filipino diagnosed and repeatedly treated medically and surgically for recurrent nasal polyposis underwent repeat endoscopic sinus surgery. A histopathologic impression of Rosai-Dorfman disease was confirmed by positive S-100 and CD1a negative immunochemistry in conjunction with the morphologic findings.CONCLUSION:
Rosai-Dorfman disease is a rare entity which should be considered when dealing with recurrent nasal polyposis that is intractable to initial medical and surgical therapies. Histopathologic findings of emperipolesis and immunohistochemical S-100 stains play a key role in the diagnosis but there is yet no definite treatment for this disease.
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Index:
WPRIM (Western Pacific)
Main subject:
Histiocytosis, Sinus
/
Emperipolesis
Limits:
Adult
/
Humans
Language:
English
Journal:
Philippine Journal of Otolaryngology Head and Neck Surgery
Year:
2014
Type:
Article
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