Therapy dose calculation in Graves disease using 4-hour I-131 uptake measurements: A retrospective study
The Philippine Journal of Nuclear Medicine
;
: 15-19, 2015.
Article
in English
| WPRIM
| ID: wpr-632931
ABSTRACT
Twenty-four-hour radioactive iodine uptake (RAIU) is commonly used to compute for therapy dose in Graves disease (GD). The purpose of this study is to determine the feasibility of using 4-hour RAIU in calculating the dose by correlating 4-hour with 24-hour RAIU and comparing the actual therapy dose using 24-hour RAIU with the computed dose using 4-hour RAIU. A total of 83 GD patients (71% female, 29% male;18-50 years old), who underwent RAI therapy at USTH Section of Nuclear Medicine, were included. There was a strong and positive correlation between 4-hour and 24-hour RAIU values (r=0.736). Paired t-test did not show a statistical difference between the actual given therapy dose based on 24-hour RAIU and the computed therapy dose using 4-hour RAIU (p 0.078). This study showed that therapy dose calculation using 4-hour RAIU can be used in Graves disease patients with no rapid turnover.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Gland
/
Graves Disease
/
Hyperthyroidism
/
Iodine
/
Nuclear Medicine
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
The Philippine Journal of Nuclear Medicine
Year:
2015
Type:
Article
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