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Lamellar ichthyosis
Journal of the Philippine Dermatological Society ; : 58-61, 2005.
Article in English | WPRIM | ID: wpr-633023
ABSTRACT
Lamellar ichthyosis is an inherited autosomal recessive disorder characterized by non-bullous erythroderma and scaling at birth. We report a patient born encased in a collodion membrane, who later developed generalized, brownish, plate-like scales, anhidrotic skin, scarring alopecia, bilateral ectropion, with a family history of similar-looking skin condition. Skin biopsy demonstrated marked lamellated orthohyperkeratosis and areas of hypergranulosis. Therapeutic trial of four topical agents (extravirgin coconut oil, urea lotion, mineral oil and petroleum jelly) was done which gave minimal improvement of scaling and dryness. Oral retinoids (Acitretin) was then initiated and yielded better results.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Petrolatum / Urea / Plant Oils / Mineral Oil / Cicatrix / Ichthyosis, Lamellar / Acitretin / Dermatitis, Exfoliative / Collodion / Ectropion Limits: Humans / Male Language: English Journal: Journal of the Philippine Dermatological Society Year: 2005 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Petrolatum / Urea / Plant Oils / Mineral Oil / Cicatrix / Ichthyosis, Lamellar / Acitretin / Dermatitis, Exfoliative / Collodion / Ectropion Limits: Humans / Male Language: English Journal: Journal of the Philippine Dermatological Society Year: 2005 Type: Article